Regular cannabis use has a negative effect on the clinical course of bipolar spectrum disorders. Individuals with bipolar spectrum disorders who are regular cannabis users are a vulnerable population.9Given the clinical significance of cannabis use in bipolar spectrum disorders, routine comprehensive and regular assessments of cannabis use are recommended. Furthermore, special attention to, and management of, patients with these substance problems must be integrated into the treatment strategy to achieve better therapeutic outcomes for bipolar spectrum disorders.
Below: Comparison of remission rates according to cannabis and tobacco use. Bar indicates median and interquartile range. *p-value<0.05, **p-value<0.01 (statistically significant after the Bonferroni correction). HAMD-21: 21-item Hamilton Depression Rating Scale, YMRS: Young Mania Rating scale.
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