Reactive arthritis is an under-studied complication of
genital Chlamydia trachomatis infection (chlamydia). We assessed trends and
risk factors for reactive arthritis in a large urban sexual health clinic.
Using a case control design, data on reactive arthritis
cases and controls at the Sydney Sexual Health Centre over the period 1992-2012
were extracted and multivariate analyses were performed. Trend analyses were
performed on reactive arthritis diagnoses.
Over the 1992-2012 study period, 85 reactive arthritis cases
were diagnosed at Sydney Sexual Health Centre. The rate of reactive arthritis
diagnoses decreased over time (23 in 1992-1996 to one in 2007-2011 and none in
2012), while chlamydia diagnoses increased (770 in 1992-1996 to 2257 in
2007-2011). In multivariate analysis, factors independently associated with a
reactive arthritis diagnosis were: being male or born overseas, while a past sexually transmissible infection
other than chlamydia or non-gonococcal urethritis was protective.
Reactive arthritis was not associated with current
or recent chlamydia infection but was marginally associated with
past non-gonococcal urethritis.
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- 1Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW, Australia Faculty of Medicine, UNSW Australia, Sydney, NSW, Australia.
- 2Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW, Australia School of Women's and Children's Health, UNSW Australia, Sydney, NSW, Australia.
- 3The Kirby Institute, UNSW Australia, Sydney, NSW, Australia.
- 4Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW, Australia School of Public Health and Community Medicine, UNSW Australia, Sydney, NSW, Australia.
- 5Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW, Australia The Kirby Institute, UNSW Australia, Sydney, NSW, Australia
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