Clinical Profile & Factors Associated with Mortality in Hospitalized Patients with HIV/AIDS: A Retrospective Analysis from Tripoli Medical Centre, Libya, 2013

In Libya, little is known about HIV-related hospitalizations and in-hospital mortality. This was a retrospective analysis of HIV-related hospitalizations at Tripoli Medical Centre in 2013. 

• Of 227 cases analysed, 
• 82.4% were males who were significantly older (40.0 versus 36.5 years), 
• reported injection drug use (58.3% versus 0%) 
• and were hepatitis C virus co-infected (65.8% versus 0%) compared with females. 
• Severe immunosuppression was prevalent (median CD4 count = 42 cell/μL). 
• Candidiasis was the most common diagnosis (26.0%); 
• Pneumocystis pneumonia was the most common respiratory disease (8.8%), 
• while cerebral toxoplasmosis was diagnosed in 8.4% of patients. 
• Current HAART use was independently associated with low risk of in-hospital mortality (OR 0.33), 
• while central nervous system symptoms (OR 4.12), 
• sepsis (OR 6.98) 
• and low total lymphocyte counts (OR 3.60) were associated with increased risk. 

In this study, late presentation with severe immunosuppression was common, and was associated with significant in-hospital mortality.

Full article at: http://goo.gl/8hfzJM

By: Shalaka NS1, Garred NA2, Zeglam HT2, Awasi SA2, Abukathir LA2, Altagdi ME2, Rayes AA1.

• 1Department of Infectious Diseases, Tripoli Medical Centre, Ain Zara, Tripoli, Libya; Department of Medicine, University of Tripoli, Ain Zara, Tripoli, Libya.
• 2Department of Infectious Diseases, Tripoli Medical Centre, Ain Zara, Tripoli, Libya.  

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