The aetiology of testicular cancer remains elusive. In this
manuscript, we review the evidence regarding the association between cannabis
use and testicular cancer development.
In this systematic review and meta-analysis, we reviewed
literature published between 1st January
1980 and 13th May
2015 and found three case–control studies that investigated the association
between cannabis use and development of testicular germ cell tumours (TGCTs).
Using meta-analysis techniques, we observed that a) current,
b) chronic, and c) frequent cannabis use is associated with the development of
TGCT, when compared to never-use of the drug. The strongest association was
found for non-seminoma development – for example, those using cannabis on at least
a weekly basis had two and a half times greater odds of developing a
non-seminoma TGCT compared those who never used cannabis (OR: 2.59, 95 %
CI 1.60–4.19). We found inconclusive evidence regarding the relationship
between cannabis use and the development of seminoma tumours. It must be noted
that these observations were derived from three studies all conducted in the
United States; and the majority of data collection occurred during the 1990’s.
Full article at: http://goo.gl/T2VreO
By: 
C. Shaw, J. Stanley, V. Signal, and D. Sarfati
C. Shaw, J. Stanley, V. Signal, and D. Sarfati
Department of
Public Health, University of Otago, PO Box 7343, Wellington, New Zealand
J. Gurney, Phone: (+64) 021 279 3597, Email: zn.ca.ogato@yenrug.nosaj.
Corresponding
author.
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