Sunday, December 20, 2015

Economic Burden of Prescription Opioid Misuse and Abuse: A Systematic Review

A 2009 systematic review found that the total cost of prescription opioid abuse in 2001 in the United States was approximately $8.6 billion and medical expenses were estimated to be $15,884 for opioid abusers and $1,830 for nonabusers. 

A search was conducted for English publications on the cost of prescription opioid abuse and misuse from 2009 to 2014. The initial literature search identified 5,412 citations. Title and abstract review selected 59 for further review. The final review process resulted in 16 publications for inclusion that examined cost from the payer perspective. 

Mean costs to the payer for abusers were $23,000-$25,000 per year and excess costs approximately $15,000 per patient. 

Three papers were identified that presented societal costs, including direct and indirect costs such as criminal justice costs and costs associated with lost productivity. The strongest evidence suggests that societal cost is in excess of $50 billion per year in the United States. 

Prescription opioid abuse and misuse is a common and important problem throughout the world that has significant associated societal costs and excess medical costs.

...Rossiter et al.21 examined a population of patients who were continuous users of extended release opioids. Overall costs were highest in commercially insured patients, $37,846, with Medicare eligible, $34,965, and Medicaid, $34,607, being lower and similar. Excess costs in each of the cohorts ranged from $9,456 to $11,501. Tkacz et al.22 compared chronic pain patients with potentially problematic opioid use (PPOU) with patients taking buprenorphine/naloxone and controls. That study found that the PPOU patients had the highest overall costs, $38,553. Buprenorphine/naloxone patients had health care costs of $28,583 and controls $26,193. Xie et al.24 evaluated patients who had been hospitalized or treated in an ED and had no prior opioid prescription in the prior 12 months and compared those who received opioids during the hospitalization or ED visit and those that did not. Patients who received an opioid during the visit had much higher overall costs than patients who did not receive an opioid ($49,766 vs. $19,875). A summary of the cost per diagnosed opioid abuse patient per year, cost per control patient, and excess cost (cost for abusers –cost for controls) is shown in Table 3...

Full article at:   http://goo.gl/roAvma




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