The introduction of
antiretroviral therapy (ART) has allowed human immunodeficiency virus (HIV)
suppression in patients. We present data of a cohort of Puerto Rican patients
with HIV who were under treatment with a steady regime of ART across a time
horizon of eleven years.
The time periods were categorized into four year
stratums: 2000 to 2002; 2003 to 2005; 2006 to 2008 and 2009 to 2011.
Socio-demographic profile, HIV risk factors, co-morbid conditions were included
as study variables. One year mortality was defined. The p value was set at
≤0.05. The cohort consisted of 882 patients with 661 subjects presenting with
persistent HIV viral load after a self-reported 12 month history of ART use. In
this sub-cohort a higher viral load was seen across time (p < 0.05). Illicit
drug use, IV drug use, alcohol use, loss of work were associated to having
higher viral load means (p < 0.05). HIV viral load mean was lower as BMI
increased (p < 0.001).
It is imperative to readdress antiretroviral
adherence protocols and further study ART tolerance and compliance.
Below: Detectable vs. non-detectable viral load (% patients)
Full article at:
- 1Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. geronimo.maldonado@uccaribe.edu.
- 2Internal Medicine Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. robert.hunter@uccaribe.edu.
- 3Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. diana.fernandez@uccaribe.edu.
- 4Microbiology Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. eddy.rios@uccaribe.edu.
- Int J Environ Res Public Health. 2015 Dec 22;13(1). pii: E50. doi: 10.3390/ijerph13010050.
- More at: https://twitter.com/hiv insight
- And: http://twitter.com/Prison Health
Excellent article!! kudos to the research team and the PI
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