Giant Molluscum Contagiosum with Granulomatous Inflammation & Panniculitis: An Unusual Clinical & Histopathological Pattern in an HIV Seropositive Child

Molluscum contagiosum is known to occur in the advanced stages of immunodeficiency in HIV infected patients and may present as atypical variants including giant molluscum. Here we describe the rare occurrence of giant molluscum contagiosum in an HIV seropositive child, which warranted surgical excision followed by skin grafting due to its unusually large size. We also highlight in this case report, a rare granulomatous inflammatory reaction pattern to molluscum with panniculitis.

Below:  Single, well defined, lobulated, tumoral swelling (5 cm × 6 cm × 7 cm in size) on the left cheek. Surface of the swelling showed few pearly white flat topped papules, ulceration with hemorrhagic crust and slough. Multiple, discrete, pearly white, umbilicated papules were present over surrounding skin

Below: The cut surface of the excised lesion showed multiple gyri like corrugations. At the base of the excised lesion, multiple pearly white papules are seen (→)

Below: Postexcision and skin grafting: Complete healing with minimal scarring

Full article at:  http://ht.ly/SZ0Da 

By: Shital Amin Poojary and Priyanka Trimbak Kokane

Department of Dermatology, Venereology and Leprology, K.J Somaiya Medical College and Research Centre, Mumbai, Maharashtra, India

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