Sunday, October 25, 2015

HIV Indicator Condition-Guided Testing to Reduce the Number of Undiagnosed Patients & Prevent Late Presentation in a High-Prevalence Area: A Case–Control Study in Primary Care

Recent guidelines advocate accelerated provider-initiated HIV testing by general practitioners (GPs). We aimed to identify the number of patient consultations in six general practices in the South-East of Amsterdam, and the incidence of HIV indicator conditions reported in their medical files prior to diagnosis.

A cross-sectional search in an electronic general practice database. We used a case–control design to identify those conditions most associated with an HIV-positive status.

We included 102 HIV cases diagnosed from 2002 to 2012, and matched them with 299 controls. In the year prior to HIV diagnosis, 61.8% of cases visited their GP at least once, compared with 38.8% of controls. In the 5 years prior to HIV diagnosis, 58.8% of HIV cases had exhibited an HIV indicator condition, compared with 7.4% of controls. The most common HIV-related conditions were syphilis and gonorrhoea. The most common HIV-related symptoms were weight loss, lymphadenopathy and peripheral neuropathy. During this period, average HIV prevalence among people aged 15–59 years increased from 0.4% to 0.9%.

This study revealed many opportunities for HIV indicator condition-guided testing in primary care. As yet, however, HIV indicator conditions are not exploited as triggers for early HIV testing.

Below:  Trends in prevalence of HIV in six general practices in a South-Eastern district of Amsterdam, the Netherlands, 2002–2012



Full article at: http://goo.gl/S5rjFl

Department of General Practice, Division of Clinical Methods and Public HealthAcademic Medical CenterAmsterdam, The Netherlands
Department of Internal Medicine, Division of Infectious DiseasesAcademic Medical CenterAmsterdam, The Netherlands
STI AIDS Netherlands (Soa Aids Nederland)Amsterdam, The Netherlands
Epidemiology & Surveillance UnitCentre for Infectious Disease Control, National Institute of Public Health and the Environment (RIVM)Bilthoven, The Netherlands
  


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