Monday, November 9, 2015

Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex with Men: Findings of a European Randomized Multi-Center Trial

Men who have sex with men (MSM) are the key population most affected by HIV in Europe. We performed the first European multicenter, simple-randomized parallel-group study to test the effectiveness of a theory-guided computer-assisted intervention to improve safer sex among HIV-positive MSM.

Between 02/2011-02/2013, 112 participants were enrolled in eight different European HIV care settings. Intervention participants received three individual counseling sessions facilitated by trained service providers using computer-assisted tools. The control-group received sexual health advice delivered as part of regular HIV care. Outcome behavior (self-reported condom use at last intercourse; combined HIV transmission risk score), its influencing factors and mediating variables were assessed at baseline, and at three and six months follow-up. Mixed effects models were used to compare primary outcomes (condom-use at last intercourse, HIV transmission risk score), and mediation analysis to explore intervention effects.

Condom-use at last intercourse increased more among intervention- than control participants at three months follow-up (odds ratio of 3.83; p=0.03), but not significantly at six months follow-up. Intervention participants reported a lower transmission risk at three months follow-up than controls (odds ratio compared to baseline of 11.53 and 1.28 respectively; p=0.008) but this effect became nonsignificant at six months. Intervention effects were mediated by the proximal variables self-efficacy to negotiate condom-use and condom attitudes.

This intervention showed short-term effectiveness. The intervention should be replicated in other settings, eventually investigating if booster-counseling sessions would yield a longer lasting effect.

Via: http://goo.gl/g7DMui  Full PDF article at: http://ow.ly/d/3Yab

  • 1Institute of Tropical Medicine, Department of Public Health; ITM's HIV AIDS Center (IHAC); Antwerp, Belgium; 2 Institute of Tropical Medicine, Department of Clinical Sciences; ITM's HIV AIDS Center (IHAC); Antwerp, Belgium; 3 Ludwig-Maximilian University, University Hospital Munich, Munich, Germany; 4 University of Zielona Gora; Zielona Gora, Poland; 5Institute of Tropical Medicine and Hygiene, Lisbon, Portugal; 6Central North West London NHS Trust; London, United Kingdom; 7 Ludwig-Maximilian University, University Hospital Munich, Munich, Germany; Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg; Freiburg, Germany; 8 AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris, France; 9 Slovak Medical University, National Reference Centre for HIV/AIDS Prevention; Bratislava, Slovak Republic; 10 Open University, Faculty of Psychology and Educational Sciences; Heerlen, The Netherlands; 11 University of Antwerp, Department of Epidemiology and Social Medicine.


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