Wednesday, October 28, 2015

On Coba & Cocok: Youth-Led Drug-Experimentation in Eastern Indonesia

The everyday lives of contemporary youths are awash with drugs to boost pleasure, moods, sexual performance, vitality, appearance and health. This paper examines pervasive practices of chemical ‘self-maximization’ from the perspectives of youths themselves. The research for this paper was conducted among male, female and transgender (male to female, so-called waria) sex workers in Makassar, Indonesia. It presents the authors’ ethnographic findings on how these youths experiment with drugs to achieve their desired mental and bodily states: with the painkiller Somadril to feel happy, confident and less reluctant to engage in sex with clients, and contraceptive pills and injectable hormones to feminize their male bodies and to attract customers. Youths are extremely creative in adjusting dosages and mixing substances, with knowledge of the (mostly positive) ‘lived effects’ of drugs spreading through collective experimentation and word of mouth. The paper outlines how these experimental practices differ from those that have become the gold standard in biomedicine...

These ethnographic case studies have revealed the pervasiveness of young sex workers’ desires to feel attractive, happy and confident; how they experiment with different drugs and modes of administration to achieve their desired effects; how experiential knowledge circulates through youth networks; and in the case of Somadril, how youths pool their resources to support their drug habits. Among the key findings is that the authors’ informants ‘try out’, or in their own words ‘coba’, different drugs and techniques to assess the effects on their bodies and minds in what may be called collective youth-led drug experiments.

The experiments involve the ‘off label’ use of prescription pharmaceuticals – that is, for purposes other than their official indication. Such experimentation is not unique to the sex workers at Losari Beach and the waria at Karebosi. The ethnographic fieldwork in Makassar revealed similar patterns of experimentation among other groups of youths. Construction workers mixed energy drinks and potency products; hard-core drug users injected a veritable cocktail into their veins in search of new highs. Students were also found to use Somadril in all kinds of different mixtures, but only on weekends and mainly to enhance sexual pleasure (Hardon, Idrus, and Hymans ).

How does the accumulation of knowledge by youth through trial and error differ from knowledge production in biomedicine? There are five main differences: first, biomedical experiments have pre-defined endpoints. Randomized controlled trials measure the effects of specific chemicals on individual bodies, with the ‘double-blind’ method ensuring that both the subjects of the experiment and those administering it do not know whether the active ingredient or an inert substance is ingested. The group receiving the inert substance is called the control group (Goldstein ). The authors’ informants feel no need for a control group; they evaluate the efficacy of products through self-observation, before and after use.

In the youth-led experiments, the subjects further determine their own desired ‘endpoints’: the development of hard tissue and a base for breasts in the case of contraceptive steroids, feeling confident in the case of Somadril. These ‘endpoints’ emerge out of the sharing of experiential knowledge on what specific drugs can do to alter their minds and bodies. The endpoints are specific to their everyday needs and desires. The wariainformants want to feminize their bodies; freelance sex workers need to be confident to approach clients.
The youth-led experiments differ from biomedical research in how they apprehend a drug's adverse effects. Biomedical researchers a priori define adverse effects and then measure them in trials. Safety and efficacy data are submitted to regulatory agencies, which then weigh the drug's benefits and risks for market approval. It is well known in pharmacology that unexpected side-effects can occur once the drug is used in routine medical practice. In contrast, youths in this study appeared unconcerned about side-effects before trying a drug for the first time. They simply tried it and observed what happens.

A fourth difference between how youth experiment with drugs and biomedical research pertains to how drugs are administered. Drugs in laboratory experiments are tested in isolation, in fixed dosages to allow for the standardized measurement of effects. Youths continuously ‘try out’ different dosages and forms of administration, mixing substances with drinks, foods and other drugs in their quest for better, stronger or faster effects.

Finally, in the biomedical measurement of drug effects, efficacy is situated in the drug's active pharmaceutical content – if substance A is proven to be effective in population B, it is assumed to work identically in population C as well. In assessing the positive and negative effects of substances in their bodies, youths in this study time and again made use of the relational notion of cocok. A drug is cocok if there is a ‘fit’ between the drug and the person taking the drug. A comparable personification of efficacy can be seen in the biomedical discipline of pharmaco-genomics, which shows how drug effects vary depending on individual genetic makeup. Such knowledge, however, still has no place in standard clinical experiments on new drugs which are generally funded by pharmaceutical companies; too much diversity would limit the market for specific drugs....

Full article at: http://goo.gl/lQAlMF

By: Anita Hardon a , * and Nurul Ilmi Idrus b
aAmsterdam Institute for Social Science Research, University of Amsterdam, Amsterdam, the Netherlands
bUniversity of Hasanuddin, Anthropology, Makassar, Indonesia
Corresponding author. Email: ln.avu@nodrah.p.a

   



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