With the increase in scaling up of antiretroviral therapy
(ART), knowledge of the need for adherence to ART is pivotal for successful
treatment outcomes.
A cross-sectional study was carried out between October and
December 2013. We administered theory of planned behaviour (TPB) and adherence
questionnaires to 358 women aged 18-49 years, from a rural and urban
ART-clinics in southern Malawi. Hierarchical linear regression models were used
to predict intentions to adhere to ART.
Regression models show that attitude (β=0.47), subjective
norm (β=0.31) and perceived behavioural control (β=0.12) explain 55% of the
variance in intentions to adhere to ART. The relationship between both food
insecurity and perceived side effects with intentions to adhere to ART is
mediated by attitude, subjective norm, and perceived behavioural control.
Household (r=0.20) and individual (r=0.21) food insecurity were positively and
significantly correlated with perceived behavioural control. Household food
insecurity had a negative correlation with perceived side effects (r=-0.11). Perceived side effects were positively
correlated with attitude (r=0.25). There
was no statistically significant relationship between intentions to adhere to
ART in the future and one month self-report of past month adherence. These
interactions suggest that attitude predicted adherence only when food
insecurity is high or perception of side effects is strong.
This study shows that modification might be needed when
using TPB constructs in resource constraint environments.
Full article at: http://goo.gl/7opxQu
School of Public Health, Loma Linda University, CA, USA
More at: https://twitter.com/hiv_insight
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