Friday, November 13, 2015

Cross Sectional Study of Factors Associated to Self-Reported Blood-Borne Infections among Drug Users

The study’s aim was to estimate the self-reported prevalence of Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV), and to describe their associated risk factors in a population of users of illicit drugs recruited in Catalonia- Spain, during 2012.

Cross-sectional study. People with illicit drugs use were selected in three different types of healthcare centres. The questionnaire was a piloted, structured ad hoc instrument. An analysis was made to identify factors associated to self-reported HCV, HIV and co-infection. Correlates of reported infections were determined using univariate and multivariate Poisson regression (with robust variance).

Among 512 participants, 39.65 % self-reported positive serostatus for HCV and 14.84 % for HIV, co-infection was reported by 13.48 %. Among the 224 injecting drug users (IDUs), 187 (83.48 %), 68 (30.36 %) and 66 (29.46 %) reported being positive for HCV, HIV and co-infection, respectively. A higher proportion of HIV-infected cases was observed among women, (18.33 % vs. 13.78 % in men). Prevalence of HCV, HIV and co-infection were higher among participants with early onset of drug consumption, long periods of drug injection or who were unemployed. A positive serostatus was self-reported by 21(7.34 %) participants who did not report any injection; among them 16 and eight, reported being positive for HCV and HIV, respectively; three reported co-infection. Only two people declared exchanging sex for money. For those that reported a negative test, the median time since the last HIV test was 11.41 months (inter-quartile range (IQR) 4–12) and for the HCV test was 4.5 months (IQR 2–7).

Among drug users in Catalonia, HIV, HCV and co-infection prevalence are still a big issue especially among IDUs. Women and drug users who have never injected drugs are groups with a significant risk of infection; this might be related to their high-risk behaviours and to being unaware of their serological status.

Full article at:  http://goo.gl/z6uwMi

By: Juliana Reyes-Urueña1234, M. Teresa Brugal45, Xavier Majo6, Antonia Domingo-Salvany2*and Joan A. Caylà1457
1Department of Paediatrics, Gynaecology and Preventive Medicine, Universidad Autónoma de Barcelona, Barcelona, Spain
2Drug Use Epidemiology Research Group, IMIM-Hospital del Mar Medical Research Institute, Dr Aiguader 88, Barcelona, 08003, Spain
3Teaching Unit of Preventive Medicine and Public Health, PSMAR-UPF-ASPB, Barcelona, Spain
4Public Health Agency of Barcelona, Barcelona, Spain
5Institute of Biomedical Research Sant Pau (IIB Sant Pau), Barcelona, Spain
6Department of Health Government of Catalonia, Barcelona, Spain
7CIBER in Epidemiology and Public Health (CIBERESP), Barcelona, Spain
 



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