Case reports in medical
literature suggest that the atypical antipsychotic quetiapine, a medication not
previously considered to have abuse potential, is now being subject to misuse
and abuse (MUA; ie, taken when not prescribed for them or used in a way other
than instructed by their health professional). Here we present systematic,
nationally representative data from the 2005 to 2011 Drug Abuse Warning Network
(DAWN) for prevalence of emergency department (ED) visits among the U.S.
general population involving quetiapine and related to MUA, suicide attempts,
and adverse reactions. Nationally, quetiapine-related ED visits increased 90%
between 2005 and 2011, from 35,581 ED visits to 67,497. DAWN data indicate that
when used without medical supervision for recreational/self-medication
purposes, quetiapine poses health risks for its users, especially among
polydrug users and women. These findings suggest that the medical and public
health communities should increase vigilance concerning this drug and its
potential for MUA.
Below: Trends in ED visits involving quetiapine for MUA, suicide
attempts, and adverse reactions: 2005–2011. Notes: *Comparing 2005 to 2011, visits are
higher in 2011 for total visits at the P < 0.001 level, for
suicide attempt visits at the P = 0.03 level, and for adverse
reaction visits at the P < 0.001 level.
Full article at: http://goo.gl/BmJYl6
By:
- 1Substance Abuse and Mental Health Services Administration, Rockville, MD, USA.
- 2Research Triangle Institute, Chapel Hill, NC, USA.
- 3Health Resources and Services Administration, Rockville, MD, USA.
More at: https://twitter.com/hiv_insight
No comments:
Post a Comment