Abstract
We assessed risk factors for
fetal death during cholera infection and effect of treatment changes on these
deaths. Third trimester gestation, younger maternal age, severe dehydration,
and vomiting were risk factors. Changes in treatment had limited effects on
fetal death, highlighting the need for prevention and evidence-based treatment.
Cholera infections during
pregnancy are associated with high rates of fetal death, especially when women
are severely dehydrated (1–7). In Haiti in 2011, pregnant women with
clinical signs of cholera who sought treatment from Médecins Sans Frontières
(MSF) in Port-au-Prince were sent to a general cholera treatment center (CTC).
In April 2012, MSF established a CTC to improve fetal outcomes in pregnant
women by facilitating intensive follow-up for dehydration and rapid access to
obstetric and neonatal services. In June 2013, a more aggressive rehydration
protocol was implemented (Technical Appendix[PDF - 112 KB - 2 pages] Table
1). To assess the effects of cholera infection, establishment of a specialized
CTC, and the new rehydration protocol, we conducted a retrospective cohort
analysis of pregnant women with suspected cholera admitted to MSF’s CTCs during
September 1, 2011−December 31, 2014....
Full article at: http://goo.gl/l2is6Y
By: 
Author affiliations: Médecins Sans Frontières,
Port-au-Prince, Haiti (E. Schillberg, L. Bryson, R. Delva-Senat);London School
of Hygiene and Tropical Medicine, London, UK (C. Ariti); Médecins Sans
Frontières, Amsterdam, the Netherlands (D. Price, A. Lenglet); Ministère
de la Santé Publique et de la Population, Port-au-Prince (R. GrandPierre)
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