Thursday, December 3, 2015

Personality Disorders among Spanish Prisoners Starting Hepatitis C Treatment: Prevalence & Associated Factors

The purpose of this study was to assess the prevalence of personality disorders (PDs) and their associated factors in prisoners who initiate chronic hepatitis C (CHC) treatment in 25 Spanish prisons. 

The Personality Diagnostic Questionnaire-4 was used to diagnose PDs according to DSM-IV criteria. Factors potentially associated with a PD diagnosis were evaluated by logistic regression analysis. Two hundred and fifty-five patients were initially assessed and 62 (24.3%) were excluded due to an incomplete or invalid self-report screening questionnaire. PD prevalence was 70.5%, with antisocial PD being the most prevalent (46.1%). In terms of PD clusters, the most prevalent was cluster-B (55.4%). 

PD diagnosis was associated with HCV genotypes 1, 2, or 3. Patients with a cluster-B PD were more likely to be infected with HCV genotypes 1, 2, or 3 and be HIV-infected, to report past-year injection drug use, and to have stage 3 or 4 fibrosis. The prevalence of PDs in Spanish prisoners who initiate CHC treatment is very high. PD management issues should be considered in treating CHC patients in prisons.

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  • 1Health Services of Barcelona Men's Penitentiary Centre, Barcelona, Spain.
  • 2Health Services of Albolote Penitentiary Centre, Granada, Spain.
  • 3Health Services of Fontcalent Penitentiary Centre, Alicante, Spain.
  • 4Health Services of Córdoba Penitentiary Centre, Córdoba, Spain.
  • 5Health Services of Sevilla Penitentiary Centre, Sevilla, Spain.
  • 6Epidemiology Service, Public Health Agency of Barcelona, CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.
  • 7Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau), CIBER de Salud Mental (CIBERSAM), Barcelona, Spain. Electronic address: jtrujols@santpau.cat. 


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