Wednesday, January 27, 2016

HIV Prevalence and Antenatal Care Attendance among Pregnant Women in a Large Home-Based HIV Counseling and Testing Program in Western Kenya

To describe the uptake of and factors associated with HIV prevalence among pregnant women in a large-scale home-based HIV counseling and testing (HBCT) program in western Kenya.

In 2007, the Academic Model Providing Access to Healthcare Program (AMPATH) initiated HBCT to all individuals aged ≥13 years and high-risk children <13 years. Included in this analysis were females aged 13-50 years, from 6 catchment areas (11/08-01/12). We used descriptive statistics and logistic regression to describe factors associated with HIV prevalence.

There were 119,678 women eligible for analysis; median age 25 (interquartile range, IQR: 18-34) years. Of these, 7,396 (6.2%) were pregnant at the time of HBCT; 4,599 (62%) had ever previously tested for HIV and 2,995 (40.5%) had not yet attended ANC for their current pregnancy. Testing uptake among pregnant women was high (97%). HBCT newly identified 241 (3.3%) pregnant HIV-positive women and overall HIV prevalence among all pregnant women was 6.9%. HIV prevalence among those who had attended ANC in this pregnancy was 5.4% compared to 9.0% among those who had not. Pregnant women were more likely to newly test HIV-positive in HBCT if they had not attended ANC in the current pregnancy (AOR: 6.85, 95% CI: 4.49-10.44).

Pregnant women who had never attended ANC were about 6 times more likely to newly test HIV-positive compared to those who had attended ANC, suggesting that the cascade of services for prevention of mother-to-child HIV transmission should optimally begin at the home and village level if elimination of perinatal HIV transmission is to be achieved.

Full article at:

By:  Ndege S1,2Washington S3Kaaria A1,4Prudhomme-O'Meara W1,2,5Were E1,6Nyambura M1Keter AK1Wachira J1,6Braitstein P1,6,7,8,9.
  • 1Academic Model Providing Access to Healthcare (AMPATH) Program, Eldoret, Kenya.
  • 2Moi University, College of Health Sciences, School of Public Health, Eldoret, Kenya.
  • 3Indiana University, School of Medicine, Indianapolis, Indiana, United States of America.
  • 4Moi Teaching and Referral Hospital, Eldoret, Kenya.
  • 5Duke University, School of Medicine and Duke Global Health Institute, Durham, North Carolina, United States of America.
  • 6Moi University, College of Health Sciences, School of Medicine, Eldoret, Kenya.
  • 7University of Toronto, Dalla Lana School of Public Health, Toronto, Canada.
  • 8Indiana University, Fairbanks School of Public Health, Indianapolis, Indiana, United States of America.
  • 9Regenstrief Institute, Inc. Indianapolis, Indiana, United States of America. 
  •  2016 Jan 19;11(1):e0144618. doi: 10.1371/journal.pone.0144618. eCollection 2016.

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