Friday, February 5, 2016

HIV Community Viral Load & Factors Associated with Elevated Viremia among Men Who Have Sex with Men (MSM) in Vancouver, Canada

We developed estimates of community viral load (VL) and risk factors for unsuppressed VL from a cross-sectional study of men who have sex with men (MSM) in Vancouver, Canada.

MSM were recruited from February 25, 2012 - February 28, 2014 using Respondent-Driven Sampling (RDS). Participants completed a computer assisted self-interview questionnaire and a nurse-administered point-of-care HIV test. For HIV positive participants, we conducted VL and CD4 cell counts. We used RDS-weighted analysis to obtain population estimates of key variables and multivariable logistic regression to examine factors associated with having a VL ≥200 copies/mL among HIV-positive participants.

We recruited 719 participants, of whom 119 (16.6%) were seeds. Our estimate of the population HIV prevalence was 23.4% (95% CI 15.8 - 31.0%) after RDS-adjustments. We estimated that 18.6% (95% confidence interval [CI] 8.8 - 30.4%) of HIV-positive MSM in Vancouver had a VL ≥200 copies/mL. Having an unsuppressed VL was associated with non-Caucasian ethnicity (adjusted odds ratio [AOR]= 4.34; 95% CI 1.67- 11.1); an annual income of <$15,000 CAD (AOR=6.43; 95%CI 2.08-19.9); using GHB in the previous six months (AOR=4.85; 95%CI 1.79-13.2); unprotected anal intercourse with a known HIV negative or unknown serostatus partner (AOR=3.13; 95%CI 1.10-8.90); and disclosing one's HIV serostatus ≥50% of the time (AOR=7.04; 95%CI 1.01-49.1).

Despite a high prevalence of HIV, we estimated that a small proportion of HIV positive MSM have undiagnosed HIV and unsuppressed VL. Our results highlight the importance of continued work to address health inequities using a social determinants of health framework.

Purchase full article at:

  • 1Department of Medicine, University of British Columbia, Vancouver, Canada 
  • 2 BC Centre for Excellence in HIV/AIDS, Vancouver, Canada 
  • 3 University of California - San Francisco, San Francisco, United States 
  • 4 University of Victoria, Victoria, Canada 
  • 5 Positive Living Society of BC, Vancouver, Canada 6Interior Health, Kelowna, Canada 7Simon Fraser University, Burnaby, Canada. 
  •  2016 Jan 27. 

Image from:

No comments:

Post a Comment