Marijuana is classified by
the Drug Enforcement Agency (DEA) as Schedule I, drugs having no accepted
medical value. Twenty-three states and the District of Columbia have legalized
medical marijuana. This conflict inhibits physicians from prescribing marijuana
and the systematic study of marijuana in medical care.
This study concerns the
use of the clinical laboratory as a resource for physicians recommending
cannabidiol (CBD) to patients, or for patients using medical marijuana.
Marijuana containing delta-9-tetrahydrocannabinol (THC) is psychoactive. CBD is
not psychoactive. CBD is reported to have medical benefit for seizure control,
neurologic disorders including multiple sclerosis, neuropathic pain and pain
associated with cancer. Use of opiates leads to increasing dosage over time
that may cause respiratory depression.
The Medical Board of California has
termed this a serious public health crisis of addiction, overdose, and death.
Is it feasible that CBD might alleviate persistent, severe pain and therefore
diminished opiate use? Further study is needed to determine medical
effectiveness of CBD including the effect on concurrent opiate therapy due to competition
for receptor sites. This study is the application of a gas chromatography mass
spectrometry procedure adapted for use in our laboratory, to detect CBD in
urine.
The intended use is as a tool for physicians to assess that marijuana
being used by a patient is of a composition likely to be medically effective. A
law ensuring physicians freedom from federal prosecution would provide
confidence essential to formal study of medical uses of marijuana and treatment
of clinical problems. Detection of CBD in a urine sample would be a convenient
test for such confirmation.
Below: Twenty-four-hour Time Study, single individual, following a single dose of CBD oil capsules
Full article at: http://goo.gl/xsE0sa
By: Paul T Wertlake and Michael D Henson
Pacific
Toxicology Laboratories, Chatsworth, CA, USA
Correspondence: Paul T Wertlake, Pacific Toxicology
Laboratories, 9348 De Soto Avenue, Chatsworth, CA 91311, USA, Emailten.nozirev@ekaltrewp
More at: https://twitter.com/hiv insight
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