Wednesday, March 23, 2016

Post-Coital Penile Washing & The Risk of HIV-Acquisition in Uncircumcised Men, in Rakai, Uganda

Post-coital genital washing by uncircumcised men may affect the risk of male HIV acquisition. We assessed the association between self-reported washing after sex in 2,976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda. 

Data from the 2,976 participants who reported sexual intercourse in the past 12 months contributed 4,290 visits, with 7316.6 person-years (py) of observation during the two-year follow-up. The overall HIV-incidence was 1.28/100py 95%CI (1.04-1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100py (95%CI 1.08-1.66), compared to an incidence of 0.62 /100py (95%CI 0.17-1.60) in men who did not wash their penis after intercourse. 

Using Poisson multivariable regression, the adjusted incidence rate ratio (AdjIRR) of HIV acquisition associated with post-coital washing was 1.94(95%CI 0.71-5.29). Post-coital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk.

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  • 1Makerere University, School of Public Health, College of Health Sciences, Kampala, Uganda 
  • b Rakai Health Sciences Program, Entebbe, Uganda 
  • c Johns Hopkins University, Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD. 
  •  2016 Mar 17.

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