Saturday, March 5, 2016

Sexual Dysfunction, Mood, Anxiety & Personality Disorders in Female Patients with Fibromyalgia

We aimed to investigate the current prevalence of sexual dysfunction (SD), mood, anxiety, and personality disorders in female patients with fibromyalgia (FM).

This case–control study involved 96 patients with FM and 94 healthy women. The SD diagnosis was based on a psychiatric interview in accordance with the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Mood and anxiety disorders were diagnosed using the Structured Clinical Interview. Personality disorders were diagnosed according to the Structured Clinical Interview for DSM, Revised Third Edition Personality Disorders.

Fifty of the 96 patients (52.1%) suffered from SD. The most common SD was lack of sexual desire (n=36, 37.5%) and arousal disorder (n=10, 10.4%). Of the 96 patients, 45 (46.9%) had a mood or anxiety disorder and 13 (13.5%) had a personality disorder. The most common mood, anxiety, and personality disorders were major depression (26%), generalized anxiety disorder (8.3%), and histrionic personality disorder (10.4%).

SD, mood, and anxiety disorders are frequently observed in female patients with FM. Pain plays a greater role in the development of SD in female patients with FM.

Current prevalence rate of SD, mood, anxiety, and personality disorders in the study groups
Patient group, n=96Control group, n=94Odds ratio (95% CI)P-value
Any sexual dysfunction46 (47.9)12 (12.8)0.15 (0.07–0.32)0.000a
Sexual desire disorder36 (37.5)13 (13.8)0.26 (0.13–0.54)0.000a
Orgasm disorder7 (7.3)1 (1.1)0.13 (0.01–1.13)0.033a
Arousal disorder10 (10.4)3 (3.2)0.28 (0.07–1.06)0.049a
Sexual aversion1 (1)00.99 (0.96–1.10)1.000b
Dyspareunia4 (4.2)1 (1.1)0.24 (0.02–2.25)0.368b
Any mood disorder27 (28.1)2 (2.1)0.05 (0.01–0.24)0.000a
Major depression25 (26)2 (2.1)0.06 (0.01–0.26)0.000b
Dysthymic disorder2 (2.1)00.97 (0.95–1.00)0.497b
Bipolar disorder00
Any anxiety disorder18 (18.8)4 (4.3)0.19 (0.06–0.59)0.002a
Generalized anxiety disorder8 (8.3)1 (1.1)0.11 (0.01–0.96)0.035b
Panic disorder2 (2.1)1 (1.1)0.50 (0.04–5.66)1.000b
Social phobia2 (2.1)1 (1.1)0.50 (0.04–5.66)1.000b
Specific phobia3 (3.1)2 (2.1)0.67 (0.11–4.12)1.000b
Posttraumatic stress disorder00
Not otherwise specified anxiety disorder6 (6.2)1 (1.1)0.16 (0.04–1.36)0.118b
Obsessive–compulsive disorder2 (2.1)1 (1.1)0.50 (0.04–5.66)1.000b
Any mood or anxiety disorder45 (46.9)5 (5.3)0.06 (0.02–0.17)0.000b
Any axis II disorder13 (13.5)5 (5.3)0.35 (0.12–1.05)0.053a
Avoidant2 (2.1)00.97 (0.95–1.00)0.497b
Dependent2 (2.1)1 (1.1)0.50 (0.04–5.66)1.000b
Obsessive compulsive1 (1)2 (2.1)2.06 (0.18–23.16)0.619b
Passive–aggressive2 (2.1)00.97 (0.95–1.00)0.497b
Histrionic10 (10.4)1 (1.1)0.09 (0.01–0.73)0.006a
Comorbidity of any psychiatric and personality disorder10 (10.4)2 (2.1)0.18 (0.04–0.87)0.019a
aχ2 test.
bFisher’s exact test. Values shown in bold are statistically significant.
Abbreviations: SD, sexual dysfunction; CI, confidence interval.

Full article at:

1Department of Psychiatry, Faculty of Medicine, Selçuk University, Konya, Turkey
2Department of Rheumatology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey
3Department of Psychiatry, Konya Numune State Hospital, Konya, Turkey
4Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Mevlana University, Konya, Turkey
5Department of Internal Medicine, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey
6Department of Neurology, Faculty of Medicine, Başkent University, Konya, Turkey
Correspondence: Fatih Kayhan, Department of Psychiatry, Faculty of Medicine, Selçuk University, Alaeddin Keykubat Campus, 42131 Selçuklu, Konya, Turkey, Tel +90 332 241 2181, Email moc.oohay@nahyakrd

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