- There is a weak association between chronic pain intensity and opioid craving.
- Patients do not crave opioids simply because they experience high levels of pain.
- Opioid craving is heightened among patients with a history of substance use problems.
- Opioid craving is also heightened among patients with high levels of negative affect.
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- 1Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, MA, USA. Electronic address: firstname.lastname@example.org.
- 2Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
- 3Division of Alcohol and Drug Abuse, Harvard Medical School, McLean Hospital, Belmont, MA, USA.
- 4Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, MA, USA.
- 5Departments of Anesthesiology and Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
- Drug Alcohol Depend. 2016 Mar 18. pii: S0376-8716(16)00153-8. doi: 10.1016/j.drugalcdep.2016.02.047
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