The Prevalence of Peyronie's Disease in the United States: A Population-Based Study

Peyronie’s disease (PD) is a connective tissue disorder which can result in penile deformity. The prevalence of diagnosed PD in the United States (US) has been estimated to be 0.5% in adult males, but there is limited additional information comparing definitive and probable PD cases. 

We conducted a population-based survey to assess PD prevalence using a convenience-sample of adult men participating in the ResearchNow general population panel. Respondents were categorized according to PD status (definitive, probable, no PD) and segmented by US geographic region, education, and income levels. 

Of the 7,711 respondents, 57 (0.7%) had definitive PD while 850 (11.0%) had probable PD. Using univariate logistic regression modeling, older age (18–24 vs 24+), Midwest/Northeast/West geographic region (South vs Midwest/Northeast/West), and higher income level (<25K vs 25K+) were each significantly associated with reduced odds of having a definitive/probable PD diagnosis compared with no PD diagnosis. When all three variables were entered in a stepwise multivariable logistic regression, only age and region remained significant. 

This study is the first to report PD prevalence by geographic region and income, and it advocates that the prevalence of PD in the US may be higher than previously cited. Further, given the large discrepancy between definitive PD cases diagnosed by a physician and probable cases not diagnosed by a physician, much more needs to be done to raise awareness of this disease.

Below:  PD prevalence by demographic subgroups

Full article at:  http://goo.gl/RBcG5m

By:  

Mark Stuntz, Anna Perlaky, Dan Glass 
Deerfield Institute, New York, New York, United States of America

Franka des Vignes 

Formerly at Deerfield Institute, New York, New York, United States of America

Tassos Kyriakides 

Yale Center for Analytical Services, Yale School of Public Health, New Haven, Connecticut, United States of America 

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Shame, Catastrophizing & Negative Partner Responses Are Associated with Lower Sexual & Relationship Satisfaction & More Negative Affect in Men with Peyronie's Disease

Introduction

Peyronie's disease (PD) has a negative impact on men's sexual functioning and quality of life, but little is known about why some men cope better than others and what the effects of PD are on their relationships. The aims of the present study were to describe negative affect, pain, relationship and sexual satisfaction in men with PD, and to explore their psychosocial correlates.

Methods

Participants were 110 men diagnosed with PD. All men completed questionnaires. Main outcome measures The main outcome measures were: Global Measure of Sexual Satisfaction, Dyadic Adjustment Scale, McGill Pain Questionnaire and Negative Affect Scale. The predictor variables were the following: Experience of Shame Scale, Body Esteem Scale, Body Image Self-Consciousness Scale, Index of Male Genital Image, a modified Pain Catastrophizing Scale and a modified Multidimensional Pain Inventory.

Results

Although men with PD had mean sexual/relationship satisfaction and negative affect scores indicating mild impairment, there was a wide range of variation, with 42-52% scoring in the clinical range. Catastrophizing was significantly associated with reduced sexual satisfaction and increased negative affect and pain. Shame was also associated with increased negative affect. The significant associations of relationship satisfaction were partner responses and shame.

Conclusions

Given the lack of curative treatment in PD, understanding why some men cope better than others may guide therapy. Shame, catastrophizing and partner responses may be important therapeutic targets.

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By:  Davis S1, Ferrar S2, Sadikaj G3, Binik Y3, Carrier S4.

• 1 Faculty of Medicine, University of Toronto , Toronto , Ontario , Canada.
• 2 Department of Psychology , Concordia University , Montreal , Quebec , Canada.
• 3 Department of Psychology , McGill University , Montreal , Quebec , Canada.
• 4 Department of Surgery, Division of Urology , McGill University Health Centre, McGill University , Montreal , Quebec , Canada.
• J Sex Marital Ther. 2016 Feb 2:0.  

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Evaluation of the Treatment of Congenital Penile Curvature Including Psychosexual Assessment

Below:  Deviation angle measurement according to Kelami. Line 1, transverse line to the base of the penis; line 2, vertical line to line 1 and gives the normal axis; line 3, transverse line at the coronal area of the penis; line 4, vertical line to line 3 and gives the deviation axis; line 5, parallel to line 1 at the junction of lines 2 and 4, the deviation angle is within 90° between lines 2 and 5

Below:  Results of depression level measured by the Beck Depression Inventory questionnaire

Study population consisted of 107 patients with congenital penile deviation (CPD) referred for surgical management. Patients were evaluated with not only clinical assessment, but also by four questionnaires measuring various aspects of quality of life. They were: Short-Form Medical Outcomes, Sexual Quality of Life Questionnaire for Man, Beck Depression Inventory, and International Index of Erectile Function.

Quality of life measurements showed deep decrease in the general quality of life, sexual performance, depression scale, as well as in physical and mental health in men with CPD. All these parameters were restored to normal after the successful surgical treatment with any method.

CPD deeply decreases the quality of life of the affected men in many aspects. Surgical treatment is able to repair the anatomical deformity and as well as significantly restore the patients' psychosocial well-being.

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