Thursday, December 24, 2015

Disparities in HIV Transmission Risk among HIV-Infected Black & White Men Who Have Sex with Men, United States

Objective
To better understand why HIV incidence is substantially higher among black than white men who have sex with men (MSM), we present the first nationally representative estimates of factors that contribute to transmission – sexual behavior, antiretroviral therapy (ART) use, and viral suppression – among HIV-infected black and white MSM in the United States.

Design
The Medical Monitoring Project (MMP) is a complex sample survey of HIV-infected adults receiving medical care in the United States.

Methods
We used weighted interview and medical record data collected during June 2009 to May 2010 to estimate the prevalence of sexual behaviors, ART use, and viral suppression among sexually active HIV-infected black and white MSM. We used χ2 tests to assess significant differences between races and logistic regression models to identify factors that mediated the racial differences.

Results
Sexual risk behaviors among black and white MSM were similar. Black MSM were significantly less likely than white MSM to take ART (80 vs. 91%) and be durably virally suppressed (48 vs. 69%). Accounting for mediators (e.g. age, insurance, poverty, education, time since diagnosis, and disease stage) reduced, but did not eliminate, disparities in ART use and rendered differences in viral suppression among those on ART insignificant.

Conclusion
Lower levels of ART use and viral suppression among HIV-infected black MSM may increase the likelihood of HIV transmission. Addressing the patient-level factors and structural inequalities that contribute to lower levels of ART use and viral suppression among this group will improve clinical outcomes and might reduce racial disparities in HIV incidence.

Below:  Antiretroviral therapy use and recent and durable viral suppression among black and white HIV-infected sexually active MSM receiving medical care – Medical Monitoring Project, United States, 2009. Recent viral suppression: most recent viral load documented ≤200 or undetectable; durable viral suppression: all viral loads past year documented less than 400 or undetectable; all black/white differences significant at P < 0.01. *95% confidence limits.



Below:  Antiretroviral therapy use among black and white HIV-infected sexually active MSM receiving medical care – Medical Monitoring Project, United States, 2009
*Adjusted for age, lapse in health coverage, poverty, time since diagnosis, and disease stage.



Below:  Durable viral suppression among black and white HIV-infected sexually active MSM receiving medical care – Medical Monitoring Project, United States, 2009
^Adjusted for age, lapse in health coverage, poverty, time since diagnosis, and education.



Full article at:   http://goo.gl/1FBQ6O

By:   Linda BeerAlexandra M. OsterChristine L. Mattson, and Jacek Skarbinski, for the Medical Monitoring Project
Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Correspondence to Linda Beer, PhD, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS-E46, Atlanta, GA 30333, USA. Tel: +1 404 639 5268; fax: +1 404 639 8640; Email: vog.cdc@reeBL
  


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