Methadone maintenance
treatment (MMT) has long been used to treat heroin-dependent patients. However,
satisfaction with methadone in this patient population is unknown. The aim of
this cross-sectional case-control study was to evaluate satisfaction with
methadone in heroin-dependent patients with current substance use disorders
(SUDs).
Cases included 152 methadone-maintained patients with current SUD,
requiring inpatient detoxification treatment, and controls included 33
methadone-maintained patients in sustained full remission for SUD. Satisfaction
with methadone as a medication to treat heroin addiction was measured by using
the Scale to Assess Satisfaction with Medications for Addiction
Treatment-methadone for heroin addiction (SASMAT-METHER).
The SASMAT-METHER
subscales assess the following domains: personal functioning and well-being,
antiaddictive effect on heroin, and antiaddictive effect on other substances.
Compared with patients with remitted SUD, patients with current SUD scored
lower on all SASMAT-METHER assessments. In such patients, overall SASMAT-METHER
scores were independently and negatively associated with downward desired
adjustment of methadone dose and days of heroin use during last month; although
various sets of factors were independently associated with each of the
SASMAT-METHER subscales, the only determinant of dissatisfaction on all
subscales was the desire for downward adjustment of methadone dose.
In summary,
MMT patients with current SUD are less satisfied with methadone than MMT
patients with remitted SUD. In patients with current SUD, downward desired
adjustment of methadone dose and days of heroin use during last month are
independently associated with overall dissatisfaction with methadone.
Purchase full article at: http://goo.gl/ti0B11
- 1From the *Addictive Behaviors Unit, Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona; †Departament de Psiquiatria i Medicina Legal, Universitat Autonoma de Barcelona, Bellaterra; and ‡CIBER de Salud Mental (CIBERSAM), Madrid, Spain
- J Clin Psychopharmacol. 2016 Jan 29.
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