Anal human papillomavirus
(HPV) infection, which is linked to anal warts and anal cancer, is common among
men who have sex with men (MSM), especially among those HIV positives.
MSM aged 18 years or older were recruited from mainland China.
Blood and anal
cytologic samples were collected for HIV-1 serological test and HPV genotyping. A total of 889
eligible participations were included. The genotyping results of HPV were
available for 822 participants (92.46%), 65.32% of which were positive for the
targeted 37 HPV types. Prevalence of infection with any type of HPV was higher
among HIV-infected participants (82.69%) as compared to HIV-uninfected participants (62.81%) (p < 0.01). HPV06
(15.45%), HPV18(13.50%), HPV16 (11.44%), and HPV11 (10.71%) were the most
frequent types identified in the study population.
Ever had paid sex with man was found to be independent predictor for HPV
positivity with an adjusted odds ratios (OR) of 2.34 (1.16-4.74). Anal HPV
positivity was observed to be independently associated with HIV infection
with an adjusted OR of 3.03 (1.76-5.21) in the study population.
In conclusion, the prevalence of anal HPV infection was observed to be common
among MSM from mainland China, and it was significantly associated with the
status of HIV infection.
Full article at: http://goo.gl/ntEi0N
- 1MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing, China.
- 2Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing, China.
- 3MSD China Holding Co., Ltd, Beijing, China.
- Sci Rep. 2016 Feb 19;6:21368. doi: 10.1038/srep21368.
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